Immunogen
Synthesized peptide derived from human ABTB1 AA range: 163-213
Specificity
This antibody detects endogenous levels of ABTB1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010],
Function
function:May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes.,similarity:Contains 2 ANK repeats.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.,
Gene Name
ABTB1 BPOZ PP2259
Human protein sequence Database
Q969K4
Mouse protein sequence database
Q99LJ2
Rat protein sequence database
Q5XIU1
Cellular localization
Cytoplasm .
Tissue expression
Ubiquitously expressed in all fetal tissues examined including heart, brain, liver, and kidney. Also expressed at lower levels in both adult heart and hypertrophic heart.
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