Immunogen
Synthesized peptide derived from human OSBP2 AA range: 86-136
Specificity
This antibody detects endogenous levels of OSBP2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2013],
Function
function:Binds 7-ketocholesterol.,similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,tissue specificity:Expressed mainly in retina, testis, and fetal liver.,
Gene Name
OSBP2 KIAA1664 ORP4 OSBPL4
Human protein sequence Database
Q969R2
Mouse protein sequence database
Q5QNQ6
Rat protein sequence database
Cellular localization
Membrane; Peripheral membrane protein.
Tissue expression
Expressed mainly in retina, testis, and fetal liver.