Immunogen
Synthesized peptide derived from human TMC2 AA range: 705-755
Specificity
This antibody detects endogenous levels of TMC2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a transmembrane protein that is necesssary for mechanotransduction in cochlear hair cells of the inner ear. Mutations in this gene may underlie hereditary disorders of balance and hearing. [provided by RefSeq, Aug 2015],
Function
function:May be required for the normal function of cochlear hair cells.,similarity:Belongs to the TMC family.,tissue specificity:Detected in fetal cochlea.,
Gene Name
TMC2 C20orf145 UNQ907/PRO1928
Human protein sequence Database
Q8TDI7
Mouse protein sequence database
Q8R4P4
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Localized to the stereocilia of the cochlear hair cells. .
Tissue expression
Detected in fetal cochlea.