Immunogen
Synthesized peptide derived from human CAP1 AA range: 71-121
Specificity
This antibody detects endogenous levels of CAP1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016],
Function
function:Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.,similarity:Belongs to the CAP family.,similarity:Contains 1 C-CAP/cofactor C-like domain.,subunit:Homodimer. Binds actin monomers.,
Human protein sequence Database
Q01518
Mouse protein sequence database
P40124
Rat protein sequence database
Q08163
Cellular localization
Cell membrane ; Peripheral membrane protein .
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