Immunogen
Synthesized peptide derived from human HHLA2 AA range: 165-215
Specificity
This antibody detects endogenous levels of HHLA2 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Function
sequence caution:Translated as Trp.,similarity:Contains 1 Ig-like C1-type (immunoglobulin-like) domain.,similarity:Contains 2 Ig-like V-type (immunoglobulin-like) domains.,tissue specificity:Expressed in colon, small intestine, lung and kidney.,
Human protein sequence Database
Q9UM44
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Expressed at high levels in colon, kidney, testis, lung and pancreas, and at lower levels in small intestine, liver and skeletal muscle. In immune cells, highly expressed in B-cells, dendritic cells and macrophages. Not detected in T-cells.