Immunogen
Synthesized peptide derived from human SSRB AA range: 107-157
Specificity
This antibody detects endogenous levels of SSRB at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [provided by RefSeq, Jul 2008],
Function
function:TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.,similarity:Belongs to the TRAP-beta family.,subunit:Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma. Interacts with TMEM173/STING.,
Gene Name
SSR2 TRAPB HSD25
Fields
>>Protein processing in endoplasmic reticulum
Human protein sequence Database
P43308
Mouse protein sequence database
Q9CPW5
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane; Single-pass type I membrane protein.
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