Immunogen
Synthesized peptide derived from human PRAP1 AA range: 84-134
Specificity
This antibody detects endogenous levels of PRAP1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:May play an important role in maintaining normal growth homeostasis in epithelial cells.,induction:Up-regulated by butyrate, trichostatin A and 5'-aza-2' deoxycytidine.,tissue specificity:Abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues.,
Gene Name
PRAP1 UPA UNQ608/PRO1195
Fields
>>Autophagy - animal
Human protein sequence Database
Q96NZ9
Mouse protein sequence database
Q80XD8
Rat protein sequence database
Q9ES75
Cellular localization
Secreted . Endoplasmic reticulum .
Tissue expression
Highly expressed in the intestinal epithelial cells (at protein level) (PubMed:32629119). Abundantly expressed in the epithelial cells of the liver, kidney and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues. Expressed in epididymis (at protein level).
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