Immunogen
Synthesized peptide derived from human CPNE4 AA range: 476-526
Specificity
This antibody detects endogenous levels of CPNE4 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene belongs to the highly conserved copine family. It encodes a calcium-dependent, phospholipid-binding protein, which may be involved in membrane trafficking, mitogenesis and development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014],
Function
function:May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties.,similarity:Belongs to the copine family.,similarity:Contains 1 VWFA domain.,similarity:Contains 2 C2 domains.,
Human protein sequence Database
Q96A23
Mouse protein sequence database
Q8BLR2
Rat protein sequence database
Cellular localization
extracellular exosome,
Tissue expression
Widely expressed (PubMed:12670487, PubMed:12949241). Expressed strongly in the brain, heart and prostate (PubMed:12670487, PubMed:12949241). Expressed strongly in peripheral blood leukocytes (PubMed:12949241).