Immunogen
Synthesized peptide derived from human CBPC5 AA range: 499-549
Specificity
This antibody detects endogenous levels of CBPC5 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a metallocarboxypeptidase involved in protein deglutamylation and a member of the peptidase M14 family of proteins. The encoded protein has been described as a "dual-functional" deglutamylase that can remove glutamate residues from both carboxyl termini and side chains of protein substrates. This deglutamylase activity may be important in antiviral immunity. Mutations in this gene are associated with retinitis pigmentosa. [provided by RefSeq, Jul 2016],
Function
similarity:Belongs to the peptidase M14 family.,tissue specificity:Expressed in brain.,
Human protein sequence Database
Q8NDL9
Mouse protein sequence database
Q09M02
Rat protein sequence database
B2GV17
Cellular localization
Cytoplasm, cytosol . Nucleus . Cytoplasm, cytoskeleton, spindle . Midbody . Mainly cytoplasmic. Slight accumulation in the nucleus is observed (By similarity). Colocalizes with alpha-tubulin in the mitotic spindle and with midbody microtubules in the intercellular bridges formed during cytokinesis. .
Tissue expression
Expressed in brain.
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