Immunogen
Synthesized peptide derived from human EHBP1 AA range: 364-414
Specificity
This antibody detects endogenous levels of EHBP1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
Function
disease:A genetic variation in EHBP1 is associated with susceptibility to hereditary prostate cancer type 12 (HPC12) [MIM:611868].,function:May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 CH (calponin-homology) domain.,subcellular location:Mostly found in cytosol and plasma membrane.,subunit:Interacts with EHD2.,
Gene Name
EHBP1 KIAA0903 NACSIN
Human protein sequence Database
Q8NDI1
Mouse protein sequence database
Q69ZW3
Rat protein sequence database
Cellular localization
Cytoplasm . Membrane . Endosome . Mostly found in cytosol and plasma membrane.
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