Immunogen
Synthesized peptide derived from human TMX1 AA range: 223-273
Specificity
This antibody detects endogenous levels of TMX1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 [PubMed 11152479]).[supplied by OMIM, Mar 2008],
Function
function:May participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions.,similarity:Contains 1 thioredoxin domain.,subcellular location:Predominantly found in the endoplasmic reticulum.,tissue specificity:Ubiquitous. Highly expressed in kidney, liver, placenta and lung.,
Gene Name
TMX1 TMX TXNDC TXNDC1 PSEC0085 UNQ235/PRO268
Human protein sequence Database
Q9H3N1
Mouse protein sequence database
Q8VBT0
Rat protein sequence database
Cellular localization
Membrane ; Single-pass type I membrane protein . Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Predominantly found in the endoplasmic reticulum. .
Tissue expression
Ubiquitous. Highly expressed in kidney, liver, placenta and lung.
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