Immunogen
Synthesized peptide derived from human ACTT1 AA range: 241-291
Specificity
This antibody detects endogenous levels of ACTT1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein related to the cytoskeletal protein beta-actin. This protein is a major component of the calyx in the perinuclear theca of mammalian sperm heads, and it therefore likely functions in spermatid formation. This gene is intronless and is similar to a related gene located on chromosome 1. A related pseudogene has also been identified approximately 75 kb downstream of this gene on chromosome X. [provided by RefSeq, May 2010],
Function
similarity:Belongs to the actin family.,
Gene Name
ACTRT1 ARPT1 HSD27
Human protein sequence Database
Q8TDG2
Mouse protein sequence database
Q9D9J3
Rat protein sequence database
Q5XIK1
Cellular localization
Cytoplasm, cytoskeleton . Cytoplasm . Nucleus . Both detected in the nucleus and cytoplasm, localizes to the nucleus where it binds chromatin upon stimulation of the Hedgehog pathway. .
Tissue expression
In skin, expressed in the basal, spinous and granular layers of the epidermis. Also expressed in hair follicles, sebaceaous glands, eccrine sweat glands and semen.
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