Immunogen
Synthesized peptide derived from human PAPD1 AA range: 445-495
Specificity
This antibody detects endogenous levels of PAPD1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011],
Function
catalytic activity:ATP + RNA(n) = diphosphate + RNA(n+1).,function:Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.,similarity:Belongs to the DNA polymerase type-B-like family.,tissue specificity:Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle.,
Human protein sequence Database
Q9NVV4
Mouse protein sequence database
Q9D0D3
Rat protein sequence database
Cellular localization
Cytoplasm . Mitochondrion .
Tissue expression
Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle.
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