Immunogen
Synthesized peptide derived from human ZN260 AA range: 64-114
Specificity
This antibody detects endogenous levels of ZN260 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
caution:It is uncertain whether Met-1 or Met-4 is the initiator.,function:Transcription factor that acts as a cardiac regulator and an effector of alpha1-adrenergic signaling. Binds to PE response elements (PERE) present in the promoter of genes such as ANF/NPPA and acts as a direct transcriptional activator of NPPA. Also acts as a cofactor with GATA4, a key cardiac regulator.,induction:Up-regulated by activation of alpha1-adrenergic receptors.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 13 C2H2-type zinc fingers.,subunit:Binds DNA. Interacts with GATA4.,
Human protein sequence Database
Q3ZCT1
Mouse protein sequence database
Q62513
Rat protein sequence database
Q62981
Cellular localization
Nucleus .