Immunogen
Synthesized peptide derived from human HP1B3 AA range: 283-333
Specificity
This antibody detects endogenous levels of HP1B3 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Component of heterochromatin, may be involved in chromatin structure and function.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the histone H1/H5 family.,similarity:In the C-terminal section; belongs to the histone H1/H5 family.,subunit:Interacts with CBX5.,
Human protein sequence Database
Q5SSJ5
Mouse protein sequence database
Q3TEA8
Rat protein sequence database
Q6P747
Cellular localization
Nucleus . Chromosome . localized in nuclei but not in nucleoli in interphase. Colocalized with chromosomes in mitosis, with a gradually increased during G1 progression and a maximum level during late G1 phase (G1/S). .