Immunogen
Synthesized peptide derived from human S17A5 AA range: 432-482
Specificity
This antibody detects endogenous levels of human S17A5
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Sialin (Membrane glycoprotein HP59) (Sodium/sialic acid cotransporter) (AST) (Solute carrier family 17 member 5)
Human protein sequence Database
Q9NRA2
Mouse protein sequence database
Q8BN82
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein .
Tissue expression
Found in fetal lung and small intestine, and at lower level in fetal skin and muscle. In the adult, detected in placenta, kidney and pancreas. Abundant in the endothelial cells of tumors from ovary, colon, breast and lung, but is not detected in endothelial cells from the corresponding normal tissues.