Immunogen
Synthesized peptide derived from human TBC21 AA range: 278-328
Specificity
This antibody detects endogenous levels of human TBC21
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
TBC1 domain family member 21
Human protein sequence Database
Q8IYX1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasmic vesicle, secretory vesicle, acrosome . Cytoplasm, cytoskeleton . Located at the edge of the acrosomal region, neck and annulus during spermiogenesis. Colocalizes with RAB3A at the acrosome-acroplaxome and neck regions of spermatids. Colocalizes with ACTB at the neck region in elongated spermatids. .
Tissue expression
Expressed in round and elongated spermatids (at protein level). Expressed specifically in adult testis and very weakly in fetal brain.