Immunogen
Synthesized peptide derived from human FNIP2 AA range: 745-795
Specificity
This antibody detects endogenous levels of human FNIP2
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
FNIP2 FNIPL KIAA1450 MAPO1
Protein name
Folliculin-interacting protein 2 (FNIP1-like protein) (O6-methylguanine-induced apoptosis 1 protein)
Fields
>>mTOR signaling pathway
Human protein sequence Database
Q9P278
Mouse protein sequence database
Q80TD3
Rat protein sequence database
Cellular localization
Lysosome membrane . Cytoplasm . Colocalizes with FLCN in the cytoplasm. .
Tissue expression
Widely expressed with highest levels in muscle, nasal mucosa, salivary gland, uvula, fat, liver, heart, placenta and pancreas (PubMed:18403135, PubMed:18663353, PubMed:27353360). Moderately expressed in the lung, small intestine, kidney and brain. Lower levels detected in renal cell carcinoma than in normal kidney tissue (PubMed:18403135). Higher levels detected in oncocytoma tumors than in normal kidney. Higher levels detected in renal cell carcinoma tumors than in normal kidney tissue (PubMed:27353360).
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