Immunogen
Synthesized peptide derived from human SUSD2 AA range: 666-716
Specificity
This antibody detects endogenous levels of SUSD2 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
similarity:Contains 1 AMOP domain.,similarity:Contains 1 SMB (somatomedin-B) domain.,similarity:Contains 1 Sushi (CCP/SCR) domain.,similarity:Contains 1 VWFD domain.,
Human protein sequence Database
Q9UGT4
Mouse protein sequence database
Q9DBX3
Rat protein sequence database
Cellular localization
Cell membrane ; Single-pass type I membrane protein . SUSD2 and LGALS1 co-localized in very specific, punctate regions along the cell membrane of breast cancer cells. .
Tissue expression
Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tissues (PubMed:25351403).
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