Immunogen
Synthesized peptide derived from human PRUNE AA range: 48-98
Specificity
This antibody detects endogenous levels of human PRUNE
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Protein prune homolog (hPrune) (EC 3.6.1.1) (Drosophila-related expressed sequence 17) (DRES-17) (DRES17) (HTcD37)
Fields
>>Purine metabolism;>>Metabolic pathways
Human protein sequence Database
Q86TP1
Mouse protein sequence database
Q8BIW1
Rat protein sequence database
Q6AYG3
Cellular localization
Cytoplasm. Nucleus. Cell junction, focal adhesion. In some transfected cells a nuclear staining is also observed.
Tissue expression
Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.