Immunogen
Synthesized peptide derived from human EHD3 AA range: 181-231
Specificity
This antibody detects endogenous levels of human EHD3
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
EHD3 EHD2 PAST3
Protein name
EH domain-containing protein 3 (PAST homolog 3)
Human protein sequence Database
Q9NZN3
Mouse protein sequence database
Q9QXY6
Rat protein sequence database
Q8R491
Cellular localization
Recycling endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, cilium membrane ; Peripheral membrane protein ; Cytoplasmic side . Localizes to the ciliary pocket from where the cilium protrudes (PubMed:25686250). Colocalizes with RAB8A and MYO5B to a cytoplasmic tubular network devoid of RAB11A (By similarity). Colocalizes with ANK2 in myocyte perinuclear region (PubMed:20489164). Colocalizes with BACE1 in tubulovesicular cytoplasmic membranes. Colocalizes with BACE1 and APP amyloid beta proteins in hippocampal mossy fiber terminals (By similarity). .
Tissue expression
Highly expressed in heart and brain and moderately expressed in kidney, liver, and placenta.
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