Immunogen
Synthesized peptide derived from human GRCR1 AA range: 132-182
Specificity
This antibody detects endogenous levels of GRCR1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells. [provided by RefSeq, Sep 2010],
Function
similarity:Belongs to the GRXCR1 family.,similarity:Contains 1 glutaredoxin domain.,
Human protein sequence Database
A8MXD5
Mouse protein sequence database
Q50H32
Rat protein sequence database
Cellular localization
Cell projection, stereocilium . Cell projection, microvillus . Cell projection, kinocilium . In the inner ear, localized to stereocilia, apical microvilli of sensory cells and kinocilia. .
Tissue expression
Expressed at low levels in adult lung, brain and duodenum with moderate levels in testis. Highly expressed in fetal cochlea.
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