Immunogen
Synthesized peptide derived from human UN13D AA range: 213-263
Specificity
This antibody detects endogenous levels of human UN13D
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Protein unc-13 homolog D (Munc13-4)
Human protein sequence Database
Q70J99
Mouse protein sequence database
B2RUP2
Rat protein sequence database
Q9R189
Cellular localization
Cytoplasm. Membrane; Peripheral membrane protein. Late endosome. Recycling endosome. Lysosome. Colocalizes with cytotoxic granules at the plasma membrane. Localizes to endosomal exocytic vesicles.
Tissue expression
Expressed at high levels in spleen, thymus and leukocytes. Also expressed in lung and placenta, and at very low levels in brain, heart, skeletal muscle and kidney. Expressed in cytotoxic T-lymphocytes (CTL) and mast cells.