Immunogen
Synthesized peptide derived from human SMRP1 AA range: 130-180
Specificity
This antibody detects endogenous levels of human SMRP1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
SMRP1 C9orf24 CBE1
Protein name
Spermatid-specific manchette-related protein 1 (Ciliated bronchial epithelial protein 1) (Testis development protein NYD-SP22)
Human protein sequence Database
Q8NCR6
Mouse protein sequence database
Q2MH31
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton . Nucleus . Cytoplasm . Localizes to the manchette in elongating spermatids (By similarity). Predominantly perinuclear in bronchial epithelial cells but also detected in the nucleus in some primary epithelial cells and in a number of cell lines. .
Tissue expression
Expressed in epithelial cells of nasal polyps and in intact epithelium of bronchial biopsies from subjects with and without asthma. Strong expression in columnar cells with little or no expression in basal epithelial cells along the basement membrane. Strongly expressed in ciliated epithelial cells with lower levels in goblet cells (at protein level).
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