Immunogen
Synthesized peptide derived from human PKHH2 AA range: 565-615
Specificity
This antibody detects endogenous levels of human PKHH2
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Gene Name
PLEKHH2 KIAA2028
Protein name
Pleckstrin homology domain-containing family H member 2
Human protein sequence Database
Q8IVE3
Mouse protein sequence database
Q8C115
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, lamellipodium . Localizes to foot process of podocytes. Localization to peripheral regions of lamellipodia seems to be dependent on PI3K.
Tissue expression
Kidney. Reduced expression in patients with focal segmental glomerulosclerosis.