Immunogen
Synthesized peptide derived from human CLCA1 AA range: 192-242
Specificity
This antibody detects endogenous levels of human CLCA1
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
Calcium-activated chloride channel regulator 1 (Calcium-activated chloride channel family member 1) (hCLCA1) (Calcium-activated chloride channel protein 1) (CaCC-1) (hCaCC-1)
Fields
>>Renin secretion;>>Pancreatic secretion
Human protein sequence Database
A8K7I4
Mouse protein sequence database
Q9D7Z6
Rat protein sequence database
Cellular localization
Secreted, extracellular space . Cell membrane ; Peripheral membrane protein ; Extracellular side . Protein that remains attached to the plasma membrane appeared to be predominantly localized to microvilli.
Tissue expression
Highly expressed in small intestine and colon namely in intestinal basal crypt epithelia and goblet cells, and appendix. Weakly expressed in uterus, testis and kidney. Expressed in the airways epithelium of both asthmatic and healthy patients. Expressed in the bronchial epithelium, especially in mucus-producing goblet cells. Expressed in normal turbinate mucosa and nasal polyp. Expressed in.
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