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CD45R Mouse mAb

Refer to | for labeled antibodies

Specification

BYab-17792

  • 50UL $180 100UL $255
  • Delivery: In Stock

Product introduction Experimental scheme Citation Related products

Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
Molecular Weight Calculated MW: 148 kDa
Immunogen
Purified recombinant fragment of human CD45R expressed in E. Coli.
Specificity
Source
Formulation
Dilution rate
WB,IHC-P,ICC/IF,FC,ELISA
Purification process (Immunogen)
Concentration
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Function
Gene Name
CD45R
Protein name
Abbreviation
Other name
Fields
Human gene ID
SwissProt ID P08575
Human protein sequence Database
Gene ID 5788
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Tissue expression
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Experimental scheme>

Procedure

Citation>

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CD45R Mouse mAb

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