Immunogen
Synthesized peptide derived from human ERO1B AA range: 23-73
Specificity
This antibody detects endogenous levels of human ERO1B
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Protein name
ERO1-like protein beta (ERO1-L-beta) (EC 1.8.4.-) (Endoplasmic oxidoreductin-1-like protein B) (Oxidoreductin-1-L-beta)
Fields
>>Protein processing in endoplasmic reticulum
Human protein sequence Database
Q86YB8
Mouse protein sequence database
Q8R2E9
Rat protein sequence database
Cellular localization
Endoplasmic reticulum membrane ; Peripheral membrane protein ; Lumenal side . The association with ERP44 may be essential for its retention in the endoplasmic reticulum.
Tissue expression
Highly expressed in the digestive tract, including the duodenum and lower digestive tract. In the stomach, highly expressed in enzyme-producing chief cells (at protein level). In the pancreas, expressed in islets of Langerhans and, at lower levels, in enzyme-secreting cells (at protein level). Detected at low level in many other tissues.
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