Molecular weight (DA)
55kD
Immunogen
Synthesized peptide derived from human Peripherin AA range: 85-135
Specificity
This antibody detects endogenous levels of Peripherin at Human, Mouse,Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.15% sodium azide.
Dilution rate
IHC-p1:50-200 ,WB 1:1000-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Peripherin(PRPH) Homo sapiens This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.
Gene Name
PRPH NEF4 PRPH1
Other name
Peripherin (Neurofilament 4)
Fields
>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
P41219
Mouse protein sequence database
P15331
Rat protein sequence database
P21807
Cellular localization
Cytoplasm, cytoskeleton . Cell projection, axon . Perikaryon .
Tissue expression
Expressed in the neurons of the outer hair cells in the organ of Corti and to a lesser extent in type I spiral ganglion cells.
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