Molecular weight (DA)
25kD
Immunogen
Synthetic peptide from human protein at AA range: 135-184
Specificity
The antibody detects endogenous Imp3 protein
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000, ELISA 1:10000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008],
Function
function:Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.,similarity:Belongs to the ribosomal protein S4P family.,similarity:Contains 1 S4 RNA-binding domain.,subunit:Component of a heterotrimeric complex containing IMP3, IMP4 and MPHOSPH10. Interacts with MPHOSPH10.,
Gene Name
IMP3 C15orf12 MRPS4
Protein name
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
Other name
IMP3 C15orf12 MRPS4
Fields
>>Ribosome biogenesis in eukaryotes
Human protein sequence Database
Q9NV31
Mouse protein sequence database
Q921Y2
Rat protein sequence database
Cellular localization
Nucleus, nucleolus .
Tissue expression
Eye,Placenta,Uterus,
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