Molecular weight (DA)
25kD
Immunogen
Synthetic peptide from human protein at AA range: 161-210
Specificity
The antibody detects endogenous CSH1 protein
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, al
Function
function:Similar to that of somatotropin.,miscellaneous:The sequence of CSH1 is shown.,similarity:Belongs to the somatotropin/prolactin family.,
Protein name
chorionic somatomammotropin hormone 1 (placental lactogen)
Human protein sequence Database
P01243
Mouse protein sequence database
Rat protein sequence database
Cellular localization
extracellular region,endoplasmic reticulum,vesicle,membrane-bounded vesicle,
Tissue expression
Placenta,Uterus,
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