Immunogen
Synthetic peptide from human protein at AA range: 1-50
Specificity
The antibody detects endogenous IL-17B
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. Alternative splicing results in multiple splice variants. [provided by RefSeq, Dec 2015],
Function
function:Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.,online information:Interleukin-17 entry,similarity:Belongs to the IL-17 family.,tissue specificity:Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.,
Gene Name
IL17B IL20 NIRF ZCYTO7 UNQ516/PRO1031
Protein name
Interleukin-17B (IL-17B) (Cytokine Zcyto7) (Interleukin-20) (IL-20) (Neuronal interleukin-17-related factor)
Other name
Interleukin-17B (IL-17B;Cytokine Zcyto7;Interleukin-20;IL-20;Neuronal interleukin-17-related factor)
Fields
>>Cytokine-cytokine receptor interaction;>>IL-17 signaling pathway
Human protein sequence Database
Q9UHF5
Mouse protein sequence database
Q9QXT6
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.
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