Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human TRAP1. AA range:481-530
Specificity
The antibody detects endogenous HSP 75
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
Function
function:Chaperone that expresses an ATPase activity.,similarity:Belongs to the heat shock protein 90 family.,subunit:Binds to the intracellular domain of tumor necrosis factor type 1 receptor. Binds to RB1.,tissue specificity:Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.,
Protein name
Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1)
Other name
Heat shock protein 75 kDa, mitochondrial (HSP 75;TNFR-associated protein 1;Tumor necrosis factor type 1 receptor-associated protein;TRAP-1)
Fields
>>Parkinson disease;>>Pathways of neurodegeneration - multiple diseases
Human protein sequence Database
Q12931
Mouse protein sequence database
Q9CQN1
Rat protein sequence database
Cellular localization
Mitochondrion . Mitochondrion inner membrane . Mitochondrion matrix .
Tissue expression
Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is highly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车