Molecular weight (DA)
100kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RHPN1. AA range:474-523
Specificity
Rhophilin Polyclonal Antibody detects endogenous levels of Rhophilin protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The PDZ domain mediates interaction with ROPN1.,function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,
Function
domain:The PDZ domain mediates interaction with ROPN1.,function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,
Other name
RHPN1; KIAA1929; Rhophilin-1; GTP-Rho-binding protein 1
Human protein sequence Database
Q8TCX5
Mouse protein sequence database
Q61085
Rat protein sequence database
Cellular localization
cytosol,
Tissue expression
Blood,Brain,
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