Immunogen
Synthesized peptide derived from human PKIG AA range: 1-80
Specificity
This antibody detects endogenous levels of human PKIG
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function
function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,tissue specificity:Ubiquitous.,
Other name
cAMP-dependent protein kinase inhibitor gamma (PKI-gamma)
Human protein sequence Database
Q9Y2B9
Mouse protein sequence database
Rat protein sequence database
Cellular localization
nucleus,cytoplasm,
Tissue expression
Ubiquitous.
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