Immunogen
Synthesized peptide derived from human COX6B2 AA range: 40-120
Specificity
This antibody detects endogenous levels of human COX6B2
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-200, ELISA(peptide)1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Background
function:Connects the two COX monomers into the physiological dimeric form.,similarity:Belongs to the cytochrome c oxidase subunit 6B family.,tissue specificity:Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.,
Function
function:Connects the two COX monomers into the physiological dimeric form.,similarity:Belongs to the cytochrome c oxidase subunit 6B family.,tissue specificity:Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.,
Other name
Cytochrome c oxidase subunit 6B2 (Cancer/testis antigen 59;CT59;Cytochrome c oxidase subunit VIb isoform 2;COX VIb-2;Cytochrome c oxidase subunit VIb, testis-specific isoform)
Fields
>>Oxidative phosphorylation;>>Metabolic pathways;>>Cardiac muscle contraction;>>Thermogenesis;>>Non-alcoholic fatty liver disease;>>Alzheimer disease;>>Parkinson disease;>>Amyotrophic lateral sclerosis;>>Huntington disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Chemical carcinogenesis - reactive oxygen species;>>Diabetic cardiomyopathy
Human protein sequence Database
Q6YFQ2
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .
Tissue expression
Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.
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