Immunogen
Synthesized peptide derived from human IER5 AA range: 28-78
Specificity
This antibody detects endogenous levels of IER5 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a protein that is similar to other immediate early response proteins. In the mouse, a similar gene may play an important role in mediating the cellular response to mitogenic signals. Studies in rats found the expression of a similar gene to be increased after waking and sleep deprivation. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the IER family.,
Gene Name
IER5 PP4583 SBBI48
Human protein sequence Database
Q5VY09
Mouse protein sequence database
O89113
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:25816751). Translocated in the nucleus during heat shock (PubMed:25816751). .
Tissue expression
Expressed in acute myeloid leukemia (AML) cells.