Immunogen
Synthesized peptide derived from human ZN473 AA range: 279-329
Specificity
This antibody detects endogenous levels of ZN473 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016],
Function
function:Involved in histone pre-mRNA processing, most likely by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 20 C2H2-type zinc fingers.,subunit:Interacts with the SLBP/pre-mRNA complex but not with SLBP alone.,
Gene Name
ZNF473 KIAA1141 ZFP100
Fields
>>Herpes simplex virus 1 infection
Human protein sequence Database
Q8WTR7
Mouse protein sequence database
Q8BI67
Rat protein sequence database
Cellular localization
Nucleus . Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA.
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