Immunogen
Synthesized peptide derived from human ICT1 AA range: 7-57
Specificity
This antibody detects endogenous levels of ICT1 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a peptidyl-tRNA hydrolase and a vital component of the large mitochondrial ribosome. The encoded protein serves as a ribosome release factor for this ribosome, which translates mitochondrial genes. This protein may be responsible for degrading prematurely-terminated polypeptides and for reusing stalled ribosomes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014],
Function
similarity:Belongs to the prokaryotic/mitochondrial release factor family.,tissue specificity:Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.,
Human protein sequence Database
Q14197
Mouse protein sequence database
Q8R035
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Down-regulated during the in vitro differentiation of HT29-D4 colon carcinoma cells.
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