Immunogen
Synthesized peptide derived from human FA72A AA range: 85-135
Specificity
This antibody detects endogenous levels of FA72A at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
induction:Up-regulated in gastric cancer.,miscellaneous:Highly homologous to GCUD2 but localized to a distinct locus.,similarity:Belongs to the FAM72 family.,
Human protein sequence Database
Q5TYM5
Mouse protein sequence database
Q8BFZ8
Rat protein sequence database
A1KXW8
Cellular localization
Cytoplasm. Mitochondrion. A V5 epitope-tagged construct has been shown to localize to the nucleus (PubMed:18676834). 5-7% of total FAM72A is associated with mitochondria around the nucleus in HEK293 cells (PubMed:21317926). .
Tissue expression
May be up-regulated in malignant colon cancers, compared to normal colon and colon adenomas. Expression is also elevated in other common cancer types, including breast, lung, uterus, and ovary.