Immunogen
Synthesized peptide derived from human CHMP7 AA range: 145-195
Specificity
This antibody detects endogenous levels of CHMP7 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
function:Plays a role in the endosomal sorting pathway.,similarity:Belongs to the SNF7 family.,subcellular location:Diffused localization, with some punctate distribution, especially in the perinuclear area.,subunit:Interacts with CHMP4B, but not with VPS25.,
Fields
>>Endocytosis;>>Necroptosis
Human protein sequence Database
Q8WUX9
Mouse protein sequence database
Q8R1T1
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus envelope . Nucleus envelope . Diffused localization, with some punctate distribution, especially in the perinuclear area (PubMed:16856878). Localizes to the reforming nuclear envelope on chromatin disks during late anaphase (PubMed:26040712, PubMed:28242692). .