Immunogen
Synthesized peptide derived from human FUZZY AA range: 92-142
Specificity
This antibody detects endogenous levels of FUZZY at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a planar cell polarity protein that is involved in ciliogenesis and directional cell movement. Knockout studies in mice exhibit neural tube defects and defective cilia, and mutations in this gene are associated with neural tube defects in humans. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012],
Function
function:May be involved in cytoskeleton function and cell polarity in epithelial cells.,similarity:Belongs to the fuzzy family.,
Human protein sequence Database
Q9BT04
Mouse protein sequence database
Q3UYI6
Rat protein sequence database
Q3B756
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, cilium basal body .