Immunogen
Synthesized peptide derived from human CNDH2 AA range: 501-551
Specificity
This antibody detects endogenous levels of CNDH2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010],
Function
function:Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CND2 H2 (condensin-2 subunit 2) family.,subcellular location:Distributed along the arms of chromosomes assembled in vivo and in vitro.,subunit:Component of the condensin-2 complex, which contains the smc2 and smc4 heterodimer, and three non SMC subunits, ncapg2, ncaph2 and ncapd3 that probably regulate the complex.,
Human protein sequence Database
Q6IBW4
Mouse protein sequence database
Q8BSP2
Rat protein sequence database
Q4V8I2
Cellular localization
Nucleus . Chromosome . Distributed along the arms of chromosomes assembled in vivo and in vitro.
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