Immunogen
Synthesized peptide derived from human ZBED6 AA range :130-190
Specificity
This antibody detects endogenous levels of ZBED6 at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this transposon-derived intronless gene is a transcriptional repressor that binds to the consensus sequence 5'-GCTCGC-3'. The encoded protein has been shown to repress IGF2 transcription. This gene is located within the first intron of the ZC3H11A gene. [provided by RefSeq, Jul 2016],
Human protein sequence Database
P86452
Mouse protein sequence database
D2EAC2
Rat protein sequence database
Cellular localization
Nucleus . Nucleus, nucleolus . Cytoplasm . Located predominantly in the nucleolus but is also dispersed throughout the nucleus (By similarity). Mainly cytoplasmic in insulin- and glucagon-positive islet pancreatic cells, however nuclear localization is evidence in some pancreatic endocrine cells (PubMed:24043816). .
Tissue expression
Expressed in pancreatic islet cells (at protein level).
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