Immunogen
Synthesized peptide derived from human MECR AA range: 160-210
Specificity
This antibody detects endogenous levels of MECR at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Function
catalytic activity:Acyl-CoA + NADP(+) = trans-2,3-dehydroacyl-CoA + NADPH.,function:Catalyzes the reduction of trans-2-enoyl-CoA to acyl-CoA with chain length from C6 to C16 in an NADPH-dependent manner with preference to medium chain length substrate. May have a role in the mitochondrial synthesis of fatty acids.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Homodimer.,tissue specificity:Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.,
Gene Name
MECR NBRF1 CGI-63
Fields
>>Fatty acid biosynthesis;>>Fatty acid elongation;>>Metabolic pathways;>>Fatty acid metabolism
Human protein sequence Database
Q9BV79
Mouse protein sequence database
Q9DCS3
Rat protein sequence database
Q9Z311
Cellular localization
[Isoform 1]: Mitochondrion .; [Isoform 2]: Cytoplasm . Nucleus .
Tissue expression
Highly expressed in skeletal and heart muscle. Expressed at lower level in placenta, liver, kidney and pancreas. Weakly or not expressed in lung.
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