Immunogen
Synthesized peptide derived from human SCRN1 AA range: 164-214
Specificity
This antibody detects endogenous levels of SCRN1 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009],
Function
function:Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium.,miscellaneous:'Secern' is an archaic English term meaning 'secrete'.,similarity:Belongs to the peptidase C69 family. Secernin subfamily.,
Human protein sequence Database
Q12765
Mouse protein sequence database
Q9CZC8
Rat protein sequence database
Q6AY84
Cellular localization
Cytoplasm .