Immunogen
Synthesized peptide derived from human ARFRP AA range: 110-160
Specificity
This antibody detects endogenous levels of ARFRP at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012],
Function
function:Possibly involved in plasma membrane-related signaling events.,similarity:Belongs to the small GTPase superfamily. Arf family.,subunit:Interacts with SYS1.,tissue specificity:Found in most tissues.,
Human protein sequence Database
Q13795
Mouse protein sequence database
Q8BXL7
Rat protein sequence database
Q63055
Cellular localization
Golgi apparatus . Golgi apparatus, trans-Golgi network . Located in the trans-Golgi in the GTP-bound active state. .
Tissue expression
Found in most tissues.