Immunogen
Synthesized peptide derived from human S36A2 AA range: 130-180
Specificity
This antibody detects endogenous levels of S36A2 at Human/Mouse/Rat
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010],
Function
function:Involved in a pH-dependent electrogenic neuronal transport and sequestration of small amino acids amino acids such as glycine, alanine and proline. Inhibited by sarcosine.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,tissue specificity:Abundantly expressed in kidney and muscle.,
Gene Name
SLC36A2 PAT2 TRAMD1
Fields
>>Protein digestion and absorption
Human protein sequence Database
Q495M3
Mouse protein sequence database
Q8BHK3
Rat protein sequence database
Q8K415
Cellular localization
Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane . Recycling endosome membrane .
Tissue expression
Abundantly expressed in kidney and muscle. Expressed in the S1 segment of the proximal tubule close to the glomerulus.
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