Immunogen
Synthesized peptide derived from human OR1P1 AA range: 65-115
Specificity
This antibody detects endogenous levels of OR1P1 at Human
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008],
Function
function:Odorant receptor .,polymorphism:A stop codon in the gene coding for this protein at position Ala-185 is responsible for functional diversity thus producing a pseudogene.. The stop codon is more frequent in non-Africans than in African-Americans.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Human protein sequence Database
Q8NH06
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane; Multi-pass membrane protein.