Immunogen
Synthesized peptide derived from human AAAT AA range: 345-395
Specificity
This antibody detects endogenous levels of AAAT at Human/Mouse
Source
Polyclonal, Rabbit,IgG
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1：500-2000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Background
The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011],
Function
alternative products:A number of isoforms are produced by alternative initiation. Isoforms start at multiple alternative CUG and GUG codons,function:Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Act as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.,
Gene Name
SLC1A5 ASCT2 M7V1 RDR RDRC
Fields
>>Protein digestion and absorption;>>Central carbon metabolism in cancer
Human protein sequence Database
Q15758
Mouse protein sequence database
P51912
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein . Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue expression
Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
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